Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies.
Identifieur interne : 000B95 ( Main/Exploration ); précédent : 000B94; suivant : 000B96Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies.
Auteurs : Jianjun Gao [République populaire de Chine] ; Zhenxue Tian [République populaire de Chine] ; Xu Yang [République populaire de Chine]Source :
- Bioscience trends [ 1881-7823 ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
- analogues et dérivés : Chloroquine.
- traitement médicamenteux : Infections à coronavirus, Pneumopathie virale.
- usage thérapeutique : Chloroquine.
- Chine, Essais cliniques comme sujet, Humains, Repositionnement des médicaments, Études multicentriques comme sujet.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- MESH :
- chemical , analogs & derivatives : Chloroquine.
- chemical , therapeutic use : Chloroquine.
- geographic : China.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- Betacoronavirus, Clinical Trials as Topic, Drug Repositioning, Humans, Multicenter Studies as Topic.
Abstract
The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine phosphate, an old drug for treatment of malaria, is shown to have apparent efficacy and acceptable safety against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. The drug is recommended to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health Commission of the People's Republic of China for treatment of COVID-19 infection in larger populations in the future.
DOI: 10.5582/bst.2020.01047
PubMed: 32074550
Affiliations:
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Le document en format XML
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Viral</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Chloroquine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Betacoronavirus</term><term>Clinical Trials as Topic</term><term>Drug Repositioning</term><term>Humans</term><term>Multicenter Studies as Topic</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Chine</term><term>Essais cliniques comme sujet</term><term>Humains</term><term>Repositionnement des médicaments</term><term>Études multicentriques comme sujet</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>République populaire de Chine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine phosphate, an old drug for treatment of malaria, is shown to have apparent efficacy and acceptable safety against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. The drug is recommended to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health Commission of the People's Republic of China for treatment of COVID-19 infection in larger populations in the future.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Gao, Jianjun" sort="Gao, Jianjun" uniqKey="Gao J" first="Jianjun" last="Gao">Jianjun Gao</name></noRegion><name sortKey="Tian, Zhenxue" sort="Tian, Zhenxue" uniqKey="Tian Z" first="Zhenxue" last="Tian">Zhenxue Tian</name><name sortKey="Yang, Xu" sort="Yang, Xu" uniqKey="Yang X" first="Xu" last="Yang">Xu Yang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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